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Finally, TNF- also confers an invasive and transformed phenotype onto tumour cells. Pre-treatment of the animals with TNF- increases lung metastases in an experimental fibrosarcoma (Orosz et al, 1993). However, neutralising endogenous TNF- with an anti-TNF- antibody reduces lung metastasis.
Saturday night and Sunday: A weak disturbance offers a 30 percent of light snow Saturday night after midnight, which might turn to light rain if it continues into Sunday morning (20 percent chance). Perhaps some of the colder suburbs could see a brief coating of snow. We keep you posted.
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